Learn more about Choline uses, effectiveness, possible side effects, CHOLINE. OTHER NAME(S). Bitartre de Choline, Chlorure de Choline, Choline. Structure, properties, spectra, suppliers and links for: choline chloride, chlorure de choline [French] [INN]. choline chloride [INN]. More CHOLINE. Choline chloride ≥99%; CAS Number: ; EC Number: ; Synonym: (2-Hydroxyethyl)trimethylammonium chloride; Linear Formula: C5H14ClNO;.
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Ullmann’s Encyclopedia of Industrial Chemistry. High doses can increase the risk of adverse effects Unlawful to download, store, or distribute content from Natural Medicines or this site.
Other names hepacholine, biocolina and lipotril.
Effort is made to ensure that the information contained in this Natural Medicines monograph is accurate at the time it was published. Preliminary clinical research suggests that taking choline orally may reduce manic symptoms and cholline mood symptoms in some lithium-treated patients with rapidly cycling bipolar disorder compared to baseline Therefore, it is possible that higher maternal intake of chlorute is needed to observe a benefit.
See separate listings for Phosphatidylcholine and Lecithin.
Orally, choline is used for liver disease including chronic hepatitis, nonalcoholic fatty liver disease, and cirrhosis. Fetal alcohol spectrum disorders FASD. However, there is evidence that oral choline does not affect concentrations of choline metabolites such as acetylcholine in the brain.
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Incompatible with strong oxidizing agents, moisture. Epidemiological evidence suggests that women who have a high dietary choline intake around the time of conception have a lower risk of having offspring with a neural tube defect compared to women with lower intake Choline is a component of phosphatidylcholine, which is a component of lecithin.
Drugs or Compounds in Development. Some researchers are interested in choline for Alzheimer’s disease because it is a precursor to acetylcholine.
It forms a deep eutectic solvent with ureaethylene glycolglyceroland many other compounds. Choline is produced in the liver via the methylation of phosphatidylethanolamine. There is concern that choline might increase the risk of colorectal cancer. Choline is added to infant formulas made from cow milk and soy Orally, large doses of choline 9 grams daily may worsen this condition Choline is safe in children when taken in doses below the tolerable upper intake level UL, which is 1 gram daily for children years of age; 2 grams daily for children years of age; and 3 chlorurr daily for children years of age In foodstuffs the compound is often present as phosphatidylcholine.
It is an important additive in feed especially for chickens where it accelerates growth. There is insufficient reliable information available about the safety of choline used in higher doses cohline pregnant or lactating women. Deficiency of choline is uncommon except in people receiving long-term total parenteral nutrition TPN A typical diet provides mg daily.
Taking choline orally seems to decrease the severity of symptoms, the number of symptomatic days and the need to use bronchodilators in patients with asthma A fholine analysis of results from observational and clinical research shows that low dietary intake of choline is associated with increased fibrosis in postmenopausal women with nonalcoholic fatty liver disease but not in children, men, or premenopausal women with this condition.
It is also used for hypercholesterolemia, depression, memory loss, Alzheimer’s disease and dementia, schizophrenia, and fetal alcohol spectrum disorders FASD. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from Natural Medicines is permitted without written permission from the publisher.
Chlorure de choline
Adding choline to the TPN solution usually improves liver function Choline also seems to play a role in the development chloruee neural tube defects There is some evidence that higher doses of 3 grams daily might be more effective than lower doses of 1.
For children years the AI is mg chkline day; years, mg per day; years, mg per day ; for infants less than 6 months, mg per day; infants months, mg per day Click to predict properties on the Chemicalize site.
Ethanaminium, 2-hyd roxy-N,N,N-trimethy l- chloride 1: Daily Upper Intake Levels UL, the highest level of intake that is likely to pose no risk of adverse effects for choline are 1 gram daily for children years, 2 grams for children years, 3 grams for children years, and 3. Preliminary clinical research shows that giving liquid choline chloride Vitamin Research Products orally at doses to achieve adequate intake AI daily for weeks does not increase plasma choline levels in infants with choline deficiency due to intestinal failure.
More research is needed to confirm this finding. Also, evidence from two observational studies shows that higher maternal intake of choline during pregnancy is not associated with improved cognitive performance in the child at the age of 3 years or 7 years; however, mean cholnie of choline in both of these studies was below the ch,orure adequate intake of mg daily May irritate eyes, skin, and respiratory tract Alfa Aesar A