ALIMTA (pemetrexed for injection) [package insert]. Indianapolis, IN: Eli Lilly and Company; Langer CJ, et al. Lancet Oncol. ;17(11) Learn how ALIMTA may help treat advanced nonsquamous non-small cell lung cancer. ALIMTA and carboplatin (carbo) is approved by the FDA to be used with an the FDA in combination with carboplatin (another chemotherapy drug) and. Read all of this leaflet carefully before you start receiving this medicine because it contains important information for you. -. Keep this leaflet. You may need to.

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Langer CJ, et al. Ibuprofen pacjage exposure AUC of pemetrexed. ALIMTA is indicated as a single agent for the maintenance treatment of patients with locally advanced or metastatic nonsquamous non-small cell lung cancer NSCLC whose disease has not progressed after four cycles of platinum-based first-line chemotherapy.

Tell your healthcare provider if you get swelling, blistering, or a rash that looks like a sunburn in an area that was previously treated with radiation.

ALIMTA® (pemetrexed): Storage of Unreconstituted Vials

Overall response rate a ORR: To view the most recent and complete version of the guidelines, go online to NCCN. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

NCCN makes no warranties of any kind whatsoever regarding their content, use, or application and disclaims any paclage for their application or use in any way. The incidences of Grade anemia, fatigue, thrombocytopenia, hypertension, alimya neutropenia were higher in patients 65 years of age and older as compared to younger patients: There is no information regarding the presence of pemetrexed or its metabolites in human milk, the effects on the breastfed infant, or the effects on milk production.


Monitor patients for inflammation or blistering in areas of previous radiation treatment. Tell your healthcare provider if you have kidney problems and take a medicine that contains ibuprofen. Scagliotti GV, et al. You are encouraged to report negative side effects of prescription drugs to the FDA.

Like cisplatin, carboplatin contains platinum. Tell your healthcare provider right away if you have any signs of infection, fever, bleeding, or severe tiredness during your treatment with ALIMTA. If you are allergic to pemetrexed, tell your doctor because you allmta not receive it.

This indication is approved under accelerated approval based on tumor response rate and progression-free survival. Accessed June 27, ALIMTA is indicated, in combination with cisplatin, for the initial treatment of patients with malignant pleural mesothelioma MPM whose disease is unresectable or who are otherwise not candidates for curative surgery. Radiation recall is a skin reaction that can happen in people who have received radiation treatment onsert the past and are treated with ALIMTA.

Based on findings from animal studies and its alimts of action, ALIMTA can cause fetal harm when administered to a pregnant woman.

ALIMTA® (pemetrexed): Storage of Unreconstituted Vials

Kidney problems, including kidney failure. Eli Lilly and Company; It is very important to take folic acid by mouth and receive vitamin B 12 injections from your healthcare provider during your treatment with ALIMTA to lower your risk of harmful side effects.


Obtain a complete blood count at the beginning of each cycle. ALIMTA is contraindicated in patients who have a history of severe hypersensitivity reaction to pemetrexed.

Go to data for additional indications. Withhold ALIMTA for acute onset of new or progressive unexplained pulmonary symptoms such as dyspnea, cough, or fever pending diagnostic evaluation. ALIMTA can cause severe myelosuppression resulting in a requirement for transfusions and which may lead to neutropenic infection.

ALIMTA® (pemetrexed for injection) | Official healthcare professionals site

If concomitant ibuprofen use cannot be avoided, monitor patients more frequently for ALIMTA adverse reactions, including myelosuppression, renal, and gastrointestinal toxicity. This may affect your ability to father a child. Tell your healthcare provider about all of the medicines you take, including inswrt and over-the-counter medicines, vitamins, and herbal supplements.

It is not known if these effects are reversible. Indications and Important Safety Information. It is not known packagw these effects on fertility are reversible. Patients with Renal Impairment: Adverse reactions observed in pediatric patients studied were similar to those observed in adults.

Severe vomiting or diarrhea can lead to loss of fluids dehydration which may cause kidney problems to become worse.